- Thoroughfares
- 100 Industrial Way
- Address Mr. Burns mentions after getting his picture with a smiling child, where's he going to meet the rich Texan. (Season 17 episode The Seemingly Never Ending Story)
- 101 Freeway
- The major freeway in Mega City.
- The major freeway in Mega City.
- 104
- Agnes closes Griddy's Doughnuts to run away with Hazel. In the car, she mentions stopping at the Wadsworth Sanctuary for lunch. Cha-Cha finds a pamphlet at Griddy's with a map. The Wadsworth Sanctuary is located on Wadsworth Road, north of Jack Pine Cove. Other landmarks on the map include the town of Jack Pine Cove, Highway 16, Highway 212, Main Street, Rain Quail B&B, and 104. (Season 1 episode I Heard a Rumor)
- 105 Freeway
- After the dome comes down, there's a store called Dome Depot for all your dome needs, located at the intersection of the 105 Freeway and the dome.
- 105th
- Address of Pete's House of Pets - 105th and decker (Season 1 episode Wild Thing)
- Street in Finch's home town of Lassiter, Iowa. (Season 3 episode Lethe)
- 10th Street
- When 8 o'clock rolls around and the same old shit is gettin' down, go to 10th Street, yeah 10th Street. If you don't want D and you don't want that crap but you gotta get the monkey off ya back, go to 10th Street, 10th Street. (Song: 10th Street)
- 11th
- The killer's text message to Zeke's father: Dad, I know who's doing this. Meet me at old soap factory on 11th.
- 12 Place
- Street listed in the phone book.
- 120
- Freeway during the car chase between the Day Family and the Night Family. (Season 6 episode Night Family)
- 125th Street
- Street in the City. (Season 1 episode My Dinner with Android)
- 12th Street
- Benny Wrights, hustler, serious tweaker, flops in a burnt-out bread factory down on 12th.
- Street on the map that Rebecca shows Theo in flashback. (Season 2 episode Sound the Alarm)
- Address - Jefferson & 12th (Season 1 episode Fine Feathered Finks)
- Where Adam's homeless date to Karl's wedding hangs out (Season 2 episode Karl's Wedding)
- Street in Springfield.
- At a city council meeting, Homer proposes a new stop sign be installed at the intersection of D Street and 12th Street. (Season 1 episode Homer's Odyssey)
- Arnie in the sky, news helicopter segment: Look out on the corner of 12th and Main, because I'm going to be sick. (Season 4 episode Marge in Chains)
- 13th
- Street Fogell mentions to the cops when they ask him where he's going - 13th and Granville.
- Street listed in the phone book.
- 14th
- Street intersection that Arnie Pie mentions during his Arnie in the Sky segment in Channel - 14th and Elm, where he dropped his bagel. (Season 3 episode Homer Alone)
- 14th Street
- Street sign being reclaimed by nature in the unnamed abandoned post-war city. (episode Two)
- Street. "You've got my lost brother's soul, my dear mother's eyes, a brown horse's mane, and my uncle's name. You walked me down 14th Street for the doctor to meet after thoughts of the grave in the home of the brave and of the weak." (Song: 14th Street / Album: Want One)
- 156th Street
- Street in Springfield that Bart passes on his journey to Milhouse's grandmother's house on 257th Street. (Season 7 episode Bart Sells His Soul)
- 15th
- The corner of Harper and 15th is where Wayne tells Tom to take $3000, which is across from Juju's Chicken Shack.
- 15th Street
- Street in Wayward Pines where Amy says she and her friends meet and walk to school - Lakewood and 15th. (Season 1 episode The Truth)
- 181st Street
- Street in Springfield that Bart passes on his journey to Milhouse's grandmother's house on 257th Street. (Season 7 episode Bart Sells His Soul)
- 18th
- Street in the Fringes where Francis' printing press is located (Season 2 episode Lessons)
- Street in Timbuktu. Segment Brad Dharma: Psychedelic Detective. (Season 3 episode 2)
- 1st
- The licensed facilitator on the pharmacotherapy world injects Maggie and Colin with Tranquol, a standard mood elevator. Disoriented, Maggie wanders in front of a bus headed for "1st & Main" in front of the Chandler Hotel. Later, a doctor gives her Troxoprine to neutralize all the drugs in her system. (Season 4 episode Just Say Yes)
- 1st Avenue
- Street in Wayward Pines, location of the house where Ethan finds the body of one of the secret service agents that went missing (after going to the address that Beverly gave him)
- 1st Street
- The devil's Needful Things antique store and Rick's curse removal service Curse Purge Plus are both located at 1st and Main in Old Town (Season 1 episode Something Ricked This Way Comes)
- 24th
- Street in Metroville, the city where the Ambiguously Gay Duo fight crime.
- 257th Street
- Street in Springfield where Milhouse's grandmother lives. (Season 7 episode Bart Sells His Soul)
- Address of guest Clare O'Neil in the Hotel registry.
- 2nd Street
- Street in Lincoln City, mentioned on police radio.
- 30th
- Bruce Matthews runs his unlicensed pharmaceutical operation from the corner of 30th and Lexington.
- 31st Avenue
- Street in Finch's home town of Lassiter, Iowa. (Season 3 episode Lethe)
- 31st Street
- There's a house listed on Jenny's real estate website located at 10254 31st St. (Season 1 episode Fairway, My Lovely)
- 34th Street
- From the title of an Itchy and Scratchy cartoon "Spherical on 34th Street”. (Season 19 episode Funeral for a Fiend)
- Street listed in the phone book.
- 3rd
- The killer creates a diversion at 3rd and Beaman to get the cops out of precinct so he can capture Angie.
- When star football player Geoff Johns kidnaps Lois, Clark and Chloe call his vehicle's navigation system company to get his location - the corner of 3rd and Grant, an empty warehouse for Hamilton MFG. (Season 4 episode Recruit)
- Street in Greendale where The Ballroom bar is located - 3rd and Water. (Season 2 episode Mixology Certification)
- 3rd Avenue
- Street sign being reclaimed by nature in the unnamed abandoned post-war city. (episode Two)
- Address on Batmanuel's Superhero License.
- Street in Finch's home town of Lassiter, Iowa. (Season 3 episode Lethe)
- 3rd Street
- Location of Plot 33 - Boxwood and 3rd. (Season 1 episode Choices)
- Street near scene of gun shop crime. (Season 2 episode Fastest Man Alive)
- Street in Springfield where Bart begins his journey to Milhouse's grandmother's house on 257th Street. (Season 7 episode Bart Sells His Soul)
- Street mentioned by the armored truck driver when they hit construction: "Hang a left on 3rd, we'll go on Liberty." Also mentioned on police radio.
- 40 SSS
- Street on Snake Planet. (Season 4 episode Rattlesnake Ricklactica)
- 40th Street
- Street on the GPS map in Mr. Incredible's car during opening chase sequence.
- 41st Avenue
- Street on the GPS map in Mr. Incredible's car during opening chase sequence.
- 42nd
- After leaving Mark's house, Petey collapses at a convenience store on 42nd. (Season 1 episode In Perpetuity)
- 42nd Street
- Street on the GPS map in Mr. Incredible's car during opening chase sequence.
- 433rd Street
- Street in Springfield. Principal Skinner's - also known as Armin Tamzarian's old neighborhood. (Season 9 episode The Principal and the Pauper)
- 43rd Street
- Street on the GPS map in Mr. Incredible's car during opening chase sequence.
- 44th Street
- There's a house listed on Jenny's real estate website located at 33 E. 44th St. (Season 1 episode Fairway, My Lovely)
- Mentioned (Season 1 episode Instant Freeze)
- 49
- Highway. Segment Brad Dharma: Psychedelic Detective. (Season 3 episode 6)
- 4th
- Street in Eureka. Young kid Jack and Zoe meet on Main Street: "I'm an Oppenheimer. The Einsteins live on 4th." (Pilot episode)
- 4th Avenue
- Street in Wayward Pines, location of local elementary school in Wayward Pines.
- Street listed in the phone book.
- 4th Street
- Max and Annie are to meet kidnappers to get Brooks at the East 4th Street bridge at midnight.
- Street in Capital City.
- Homer finds a hidden message from his fugitive mother Mona in the newspaper. "Homer, meet me 4th street overpass midnite" (Season 15 episode My Mother the Carjacker)
- (Season 2 episode Dancing' Homer)
- 510
- Highway on the map that Audrey gives Dalton.
- 54th
- Street mentioned over the PA while Philbert Noyce rides the train - "Transfer to Pink Line trains at 54th and Cermak". (Episode Kill All Others)
- 57th Street
- Mentioned (Season 1 episode Instant Freeze)
- 59th Street
- Mentioned (Season 1 episode Instant Freeze)
- 5th
- Address of the party that Seth and Evan crash (5th and Paysview)
- Street name mentioned. (episode The Butler Did It)
- Location of Armored car being robbed - 5th and Main - announced over the police speaker during the softball game between the police team and the power plant team. (Season 3 episode Homer at the Bat)
- Address of Jones Chemical, the company that Connor helps Garrett's team rob. Also where the No Fly zone starts - Main and 5th.
- 5th Avenue
- Street in Wayward Pines, location of local elementary school in Wayward Pines.
- Street in Finch's home town of Lassiter, Iowa. (Season 3 episode Lethe)
- 5th Street
- When Dr. Yedlin wakes up in Wayward Pines, Kerry takes him to the hospital, first confirming if 7th Street is clear. Response is Negative. She is advised to take 5th over to Cherry Blossom. (Season 2 episode Enemy Lines)
- Mentioned (Season 1 episode Instant Freeze)
- Street in The Citadel of Ricks. Address of Morty Mart in the Citadel of Ricks, mentioned on the police radio. (Season 3 episode The Ricklantis Mixup)
- 61
- Highway. Segment Brad Dharma: Psychedelic Detective. (Season 3 episode 6)
- 6th Avenue
- Song: 6th Avenue Heartache.
- Street in Central City.
- Street in Finch's home town of Lassiter, Iowa. (Season 3 episode Lethe)
- 6th Street
- Street that Lightning Electronics store is on.
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