- Computers
- A-7
- Security Systems' artificial intelligence (Season 1 episode Security Systems)
- The Administrator
- A.I. running the Heaven's River topopolis. (Heaven's River)
- Agnes
- The world's most advanced electronic computer. (episode From Agnes - With Love)
- ANDI
- A.I. created by a defendant. Artificial Neuron Developed intelligence. (Season 6 episode Night Court of the Living Dead)
- Anek-23
- The A.I. behind the Heaven's River topopolis, taking care of the Quinlan people. (Heaven's River)
- Archos R-14
- A computer scientist accidentally unleashes a supremely intelligent sentient A.I. named Archos R-14. It becomes self-aware and immediately starts planning the elimination of human civilization and building a new cryptic ecology, where the organic is being merged with robot technology.
- ARTI
- Also known as The ARTI Initiative. The United Space Planetary Corporation's Artificial Intelligence support system.
- B.E.N.
- Artificial Intelligence on the Seraphim space station.
- Bob
- NSA cybernetic supercomputer. (Season 1 episode Bob)
- Boob-a-Tron 4000
- Machine Abed builds to create college hijinks. (Season 1 episode The Art of Discourse)
- Brainchild
- Broots, Miss Parker and Sydney find an old Brainchild, one of the first generations of supercomputers, abandoned down in Sub Level 27. (Season 1 episode The Dragon House)
- BUFFY
- A.I. controlling Fargo's Mu-Tent. Bio-mechanical Unfolding Fully-Automated Yurt. (Season 4 episode Momstrosity)
- The Calico Supercomputer
- The evil Dr. Calico's computer.
- The Combine
- This is Chief's word to describe the machine-like nature of the asylum system. But it's not just the asylum that's governed by this machine - it's the entire world. He can hear its hum in the walls. Often, Nurse Ratched represents the authority of the Combine; she is the public face of an inhumane system.
- Control
- Section 31's threat assessment system, fed data from every Star Trek admiral. It seeks all of the data that the sphere collected on artificial intelligence from countless civilizations as road map to become fully conscious. (Season 2 episode Project Daedelus)
- Decatronics Turbo Graphics II Workstation
- Technology at the bomb squad office where Jarod pretends to be a bomb expert, capable of producing aged images of suspects, which Jarod asks his co-worker to use on a photo of his mother. (Season 1 episode Potato Head Blues)
- Deep Thought
- The computer asked to determine the Answer to the Ultimate Question of Life, the Universe and Everything.
- The supercomputer that provides the answer to the ultimate question about life, the universe and everything, which is "42".
- A gigantic supercomputer created to calculate once and for all the Answer to the Ultimate Question of Life, the Universe, and Everything.
- DemoPol
- New record added 3/25/2023
- Generations ago, a secret, unauthorized experiment by the Gowachins was carried out with the help of a contract with the Calebans. They isolated the planet Dosadi behind an impenetrable barrier called "The God Wall". On the planet were placed humans and Gowachin, with an odd mix of modern and old technology. The planet itself is massively poisonous except for a narrow valley, containing the city "Chu", into which nearly 89 million humans and Gowachin are crowded under terrible conditions. It is ruled by a dictator, many other forms of government having been tried previously, but without the ability to remove such things as the DemoPol, a computer system used to manipulate populaces without their consent or knowledge. The culture of ordinary day-to-day power in Dosadi is very violent. Among other tools, addictive psychotropes are used for handling power among hierarchies in organisations.
- Dory
- Artificial intelligence computer program within the Grid. Also referred to as a "binary algorithm wrapped in a computer projection". (Season 7 episode The Grid)
- The Earth
- The even bigger computer that had to be built to find out the Ultimate Question of Life, the Universe, and Everything.
- Eddie
- The Heart of Gold's shipboard computer.
- The Heart of Gold's shipboard computer.
- Shipboard computer on the Heart of Gold.
- EMERAC
- New record added 3/25/2023
- Methods Engineer and efficiency expert Richard Sumner is the inventor of EMERAC - Electromagnetic MEmory and Research Arithmetical Calculator, nicknamed “Emmy,” a powerful early generation computer referred to then as an “electronic brain”. He is brought in to see how the library functions, and size it up for installation of one of his massive machines.
- Emma
- Computer at the National Testing Center that processes the Career Aptitude Normalizing Test results. (Season 3 episode Separate Vocations)
- F.R.I.D.A.Y.
- The natural-language user interface that Tony Stark uses after J.A.R.V.I.S. is used to create Vision.
- Tony Stark's natural-language user interface for his Iron Man suit.
- Tony Stark's natural-language user interface for his Iron Man suit.
- Tony Stark's natural-language user interface for his Iron Man suit.
- FeMac Computer
- Although Homer makes several attempts to cheat - which he calls "Operation Slight Edge", Ned Flanders' duck comes in first in the Rubber Duck Race at Game at Reverend Lovejoy's Church Fundraiser, winning him a feMac computer, the computer designed just for women, which he gives to Marge in exchange for her babysitting Rod and Todd while he attends the Left Handers Convention. The "You've got mail" voice is Susan Sarandon. (Season 17 episode Bart Has Two Mommies)
- Foobar Model 37 Computer
- A fictional computer is mentioned: A Foobar model 37 computer, and we're trying to hook up a Yoyodyne tape to it.
- Frinkiac 7
- Computer that Professor John Frank invents. (Season 7 episode Much Apu About Nothing)
- G.E.E.C.
- Goodfellow's Effort-Eliminating Computer. When machines start operating by themselves, the Government asks the Justice League of America to investigate. The heroes arrive at G.E.E.C., where Professor Goodfellow shows the Super Friends his G.E.E.C. invention, which would free everyone of work and responsibility. (Season 1 episode Professor Goodfellow's G.E.E.C.)
- G.I.N.A.
- The Woods family personal home A.I. system and helper.
- The G.R.T.A.
- Also known as Gertie,. A.I. supercomputer at Neberdine.
- Glenn
- Artificial intelligence computer program within the Grid. Also referred to as a 'binary algorithm wrapped in a computer projection'. (Season 7 episode The Grid)
- God's Eye
- A tracking device on steroids. God's Eye hacks into anything that's on the digital network - that means every cell phone, satelliteTM machine and computer simultaneously. If it's got a microphone or a lens, God's Eye can use it.
- H.A.L. 9000
- Discovery One's shipboard computer.
- Hactar
- A gigantic spaceborne computer, which to this day is remembered as one of the most powerful ever built.
- HARDAC Machine
- Machine that creates mechanical replicants to replace existing humans, with the ultimate goal of replacing all humans. The scientist that created the machine is named Karl Rossum, named for Rossum's Universal Robots in Karel Čapek's play R.U.R. One of the robots is seen driving a car with "RUR" as the license plate number. (episode Heart of Steel)
- HOLMES IV
- Also known as High-Optional, Logical, Multi-Evaluating Supervisor, Mark IV. The Lunar Authority's master computer that becomes self-aware and develops a sense of humor. Nicknamed Mike, after Sherlock Holmes' brother.
- HyperPro PC
- Chronowerx Industries' new computer. (Season 3 episode Future's End)
- IBN 5100
- Old pre-BASIC home computer system.
- Info Cram 6000
- Professor Frink invention, with which you can absorb books instantly by attaching an electrode to the brain pan and another one to the loins. (Season 12 episode Insane Clown Poppy)
- IVAN
- Internal Voice Activated Navigator on Buzz Lightyear's ship.
- J.A.R.V.I.S.
- Tony Stark's natural-language user interface computer system, named after Edwin Jarvis, the butler who worked for Howard Stark.
- Just A Rather Very Intelligent System. Tony Stark's natural-language user interface computer system.
- JEH Power Computer
- Wade uses a JEH Computer at Doppler Computer Superstore where she used to work to find out what's on the chip that Judge John Nassau gave her before he died. While she's there, the clerk suggests another computer if the Tolson's too slow. (Season 2 episode Time Again and World)
- Johnny
- Computer that does the math for each trip through the Albuquerque Door.
- JOVA
- Also known as Judicious Omnicompetent Volitional Adaptive. Hugh and the Skippies' Matrioshka brain project. (Heaven's River)
- K.E.V.I.N.
- Knowledge Enhanced Visual Interconnectivity Nexus. Artificial intelligence responsible for making all of the decisions regarding the Marvel Cinematic Universe. Unhappy with the way her finale is playing out, Jen punches her way into the real world and confronts her writers. (Season 1 episode Whose Show is This?)

- KL-5
- Computer system that Chandler mentions during his interview, shortly before talking about his duties: "I was the point person on my company's transition from the KL5 to GR6 systems." (Season 8 episode The One With the Cooking Class)
- Kronos
- A super computer created by VA Industries, designed to end all wars. When Kronos goes online, it quickly determines that mankind, itself, is the biggest threat to world peace and launches a worldwide robot attack to rid the world of the infection of man.
- Kutuzov Computer
- Orlov: In East Germany under my direct command, I have 31 divisions, including 11 tank divisions and another five in Czechoslovakia. In support, on the Russian western border are 60 divisions, including 22 tank divisions. In all, a 10-1 advantage. American and West German forces can field at most ten armoured divisions. The British maintain only a token force. We have played out a variety of attack strategies on the new Kutuzov computer and find that a lightning thrust by ten armored divisions from the north, and by five more through Czechoslovakia, lead to total victory in five days against any possible defense scenario.
- L-329
- A.I. in charge of BTC Russia.
- Legion
- The new Skynet, since Sarah and John destroyed it in T2 Judgment Day.
- Lucy
- Artificially Intelligent spaceship owned by Dutch and used as interplanetary transportation and working/living space for her Killjoy team.
- M-4
- Matthew's control computer. (Episode The Judas Goat)
- The Machine
- The computer system Harold Finch and Nathan Ingram built as part of the secret government operation Northern Lights - an artificial super intelligence designed to predict and prevent imminent terrorist attacks.
- Macintosh 8000 CX
- Fake computer model Norm comes up with when he's acting like the fake boss he made up - Kreitzer (Season 8 episode The Two Faces of Norm)
- MENTOR
- The Pentaverate's computer. The greatest supercomputer in the world with a human soul that's wicked smart. (Season 1 Episode 1)
- Mobile Crime Computer
- Batman's mobile crime computer in the Batmobile.
- Mother
- Colonization vessel Covenant's A.I. pilot.
- The consciousness that destroys humanity in order to save it.
- MU/TH/UR 6000
- Also known as Mother. Artificial intelligence computer aboard the USCSS Nostromo.
- N.E.P.T.U.N.E.
- The Navy Engineers Power Tower Nuclear Energy. The artificial intelligence that oversees the Sea of Lost Spaceships. (Season 1 episode Sword in a Hole)
- Navi-computer
- Computer that Buzz mentions.
- Nexus
- A self-aware computer virus controlling the New Paradigm.
- O.B.I.T.
- Peeping Tom data processing computer. "Outer Band Individuated Teletracer”(Episode O.B.I.T.)
- Octium 4
- 6.8 gigaflops, 7 billion calculations per second.
- OoGhiJ MIQtxxXA
- A supercomputer originally designed by Frylock, it was accidentally sent back in time and discovered by a caveman, who used it to evolve and then patented it.
- Precursor Virus
- The A.I. known as Archos R-14 infects all penetrable networked electronic devices, such as cars, airplanes, smart homes, elevators, and other robots, with the precursor virus.
- R.O.K. 4000
- The Airplane equivalent of HAL 9000 from Kubrick's 2001: A Space Odyssey.
- Raquel
- Computer genius, anti-deodorant activist, and millionaire Russell Borchert's computer, a machine that can process feelings. (Season 5 episode Basic Sandwich)
- Red Queen
- Original A.I. from the Hive in the first movie that goes homicidal and attempts to kill all residents of the Hive in order to contain the infection.
- The Red Queen
- Mentioned during Alice's recap: The computer that controlled the Hive, a state of the art artificial intelligence that responded to the threat of the viral outbreak in an extreme way. She went homicidal. The Red Queen attempted to kill everyone, whether they were infected or not.
- To help him control the now vast interests of the Umbrella Corporation, Dr. Isaacs created a powerful artificial intelligence. Isaacs used the likeness of Professor James Marcus' daughter, Alicia Marcus for the computer's interface.
- State-of-the-art artificial intelligence. She is the computer that controls the Hive.
- Rehoboam
- The advanced AI that controls Incite Inc., the data collection and analysis company that watches and analyzes human subjects. (Season 3 episode Parce Domine)
- S.A.N.D.E.R.S.
- Dean Pelton brings the study group in to wash the Winnebago turned space simulator known as the Eleven Herbs & Space Experience, originally sponsored by Kentucky Fried Chicken and used as a special attraction at the Greendale County Museum back in the 1980's. The vehicle is controlled by the Systematic Android Network Diode Energy Rocket System, also known as S.A.N.D.E.R.S. (Season 2 episode Basic Rocket Science)
- Samaritan
- The second super computer A.I. after the Machine designed to prevent acts of terror after 9/11.
- SARAH
- A.I. controlling Sheriff Carter's Smart House.
- SIGORN-E
- Also known as Simulated Intelligence Guardian of Residence and Network Environment. A.I. security system in J.C.C., James Cameron's compound. (Season 1 episode Pandora's Mailbox)
- Skynet
- The first self-aware computer system.
- SkyNet
- Machine computer.

- Skynet
- AI that takes over Cyberdine Systems. (T2-3D: Battle Across Time attraction)
- The U.S. missile defense system that declares war on mankind and triggers a nuclear apocalypse. (Season 1 Pilot episode)
- The A.I. that tries to wipe out humanity in the original timeline, now a new entity known as Legion.
- The digital defense system built by the government's Cyber Research Systems.
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